Some projects are long-lasting

The text below was originally posted in March 2021 or so, but the blogger removed it, because inappropriate content! OK, I've got it, it was done by a robot, since it was then restored by the blogger team. In future, I need to select my words more wisely! 😂

 ---------------------------

I had an idea a long time ago, I cannot recall it exactly, but somewhere around 2012-2013. Then we needed to get a funding to execute the idea, that actually took relatively short period of time, as we were able to include that idea to a part of a grant that was about the be awarded at the same time in 2014. Then the real work started. After failed attempts, we finally gained a lot of nice data during 2015-2016, but the original hypothesis was not met, which meant that the publications was very hard to conclude or even write about, not to mention how hard it was to be accepted and published. Well, the most of the time we spend thinking how to pull everything together, and that took roughly 3 years. 😆 OK, I think everyone of us just wanted to forgot the project. But in 2019, we activated and started to write the manuscript and in 2020 we submitted the first version, which gained a lot of critic, of course, but I must thank for the reviewers, as this time (which definitely doesn't happen too often these days) we got a very constructive feedback that help us a lot to improve the content of the manuscript. And to our surprise the second attempt only the the second journal choice of us (International Journal of Pharmaceutics) was successful and this paper is now out to be read, in 2021. So from the idea to published results and communication, it took 8-9 years. But well done team! Thank you for all the co-authors for your efforts, mainly to the corresponding one, Aaro!

If you want to find out what is was all about, the final conclusion was that there is species differences in intrabrain distribution of L-type amino acid transporter 1 (LAT1)-utilizing prodrugs between mice and rats, but mainly because of the expression and localization of bioconverting enzymes rather than expression levels of LAT1 in the brain. 

See more from this link.