Make it double!

A weird thing happened a week ago. And I bet it would never happen again. On the same day, I have got 2 acceptance letters of the submitted articles, in a row! Well, the easy explanation for this is that 2 manuscripts were submitted to the same journal, although at different times, but the reviewing process varied so much that they were accepted finally at the same time, and most likely will be published in the same issue of Journal of Pharmaceutical Sciences. 

The first one, for which I was the corresponding author is:

Improved L-Type Amino Acid Transporter 1 (LAT1)-Mediated Delivery of Anti-Inflammatory Drugs into Astrocytes and Microglia with Reduced Prostaglandin Production (link for the publication)

Here we synthesized 4 LAT1-utilizing ester prodrugs of non-steroidal anti-inflammatories (NSAIDs) and studied the relatioships between the structure and the release of the parent drug, to improve the pharmacokinetic profile and the delivery of NSAIDs into the brain via LAT1 and finally the pharmacological profile (inhibition of prostaglandins). Many of my visiting ERASMUS students were participating to this project, so thank you all for your great contribution!

The other publication is something that I was honored to be co-authoring, as my contribution was really minor in this one:

Oral Genistein-loaded Phytosomes with Enhanced Hepatic Uptake, Residence and Improved Therapeutic Efficacy against Hepatocellular Carcinoma (link for the publication)

I have not much to say about this marvelous publication, as phytosomes are not my core experties, but I must admit that it was a great to learn about them and be part of this project that have potential to improve cancer chemotherapy with these nanoparticles! So thank you for all the co-author of this publication!