Janne's 2. publication out!

We got really goods new last week and the final process was very fast, so the publication number 2 for Janne's Ph.D. thesis is now out! Congratulations Janne and thanks for all the co-authors for your great contribution! 🌹 The publication under the title "The L-type amino acid transporter 1 enhances drug delivery to the mouse pancreatic beta cell line (MIN6) (link, open access)" was published in prestigious European Journal of Pharmaceutical Sciences and continued Janne's work on LAT1 transporter expression and utilization in pancreatic beta-cells. So from the 1. publication's tissue level, we proceeded on the cellular level. 

Personally I find the correlation between in vitro cellular uptake and in vivo pancreatic accumulation of our LAT1-utilizing prodrugs (of several non-steroidal anti-inflammatory drugs) as the most fascinating result, but of course Janne made great work with the prodrugs, and showed that they were able to revert cytokine-induced effects on insulin secretion, and balance other biomarkers, identified in global proteomic analysis that were measured by liquid chromatography-mass spectrometry (LC-MS). So great work and lots of things learned for the future!